| OT Roger Rosengarten - Ankle, Limited Practice on Wednesday. Questionable for Week 6 vs. Washington |
G Nick Allegretti - Ankle, Did Not Practice on Wednesday. Questionable for Week 6 at Baltimore |
| CB Marlon Humphrey - Ankle, Did Not Practice on Wednesday. Questionable for Week 6 vs. Washington |
LB Dante Fowler - Illness, Did Not Practice on Wednesday. Questionable for Week 6 at Baltimore |
| OT Ronnie Stanley - Toe, Did Not Practice on Wednesday. Questionable for Week 6 vs. Washington |
RB Brian Robinson Jr. - Knee, Did Not Practice on Wednesday. Questionable for Week 6 at Baltimore |
| TE Charlie Kolar - Toe, Limited Practice on Wednesday. Questionable for Week 6 vs. Washington |
RB Austin Ekeler - Heel, Limited Practice on Wednesday. Questionable for Week 6 at Baltimore |
| WR Deonte Harty - Knee, Limited Practice on Wednesday. Questionable for Week 6 vs. Washington |
SAF Percy Butler - Groin, Limited Practice on Wednesday. Questionable for Week 6 at Baltimore |
| WR Rashod Bateman - Groin, Did Not Practice on Wednesday. Questionable for Week 6 vs. Washington |
CB Jartavius Martin - Neck, Questionable for Week 6 at Baltimore |
| LB Malik Harrison - Groin, Did Not Practice on Wednesday. Questionable for Week 6 vs. Washington |
WR Noah Brown - Groin, Limited Practice on Wednesday. Questionable for Week 6 at Baltimore |
| DT Broderick Washington - Knee, Did Not Practice on Wednesday. Questionable for Week 6 vs. Washington |
DE Clelin Ferrell - Knee, Did Not Practice on Wednesday. Questionable for Week 6 at Baltimore |
| RB Rasheen Ali - Neck, IR. Injured Reserve. Expected Return - Week 6 |
DB Tyler Owens - Shin, Did Not Practice on Wednesday. Questionable for Week 6 at Baltimore |
| CB Arthur Maulet - Knee, IR. Injured Reserve. Expected Return - Week 6 |
DE Efe Obada - Lower Leg, Physically Unable to Perform. Expected Return - Week 6 |
| CB Jalyn Armour-Davis - Hamstring, IR. Injured Reserve. Expected Return - Week 8 |
LB Jordan Magee - Knee - Meniscus, IR. Injured Reserve. Expected Return - Week 6 |
| LB Deion Jennings - Undisclosed, IR. Injured Reserve |
WR Jamison Crowder - Calf, IR. Injured Reserve. Expected Return - Week 9 |
| CB Trayvon Mullen - Shoulder, IR. Injured Reserve |
DT Norell Pollard - Undisclosed, IR. Injured Reserve |
| CB Christian Matthew - Undisclosed, IR. Injured Reserve |
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| LB Malik Hamm - Knee - ACL, IR. Injured Reserve |
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| RB Keaton Mitchell - Knee - ACL, Physically Unable to Perform. Expected Return - Week 9 |
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| RB Owen Wright - Foot, IR. Injured Reserve |
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