| G Nick Allegretti - Ankle, Did Not Practice on Wednesday. Questionable for Week 6 at Baltimore |
OT Roger Rosengarten - Ankle, Limited Practice on Wednesday. Questionable for Week 6 vs. Washington |
| LB Dante Fowler - Illness, Did Not Practice on Wednesday. Questionable for Week 6 at Baltimore |
CB Marlon Humphrey - Ankle, Did Not Practice on Wednesday. Questionable for Week 6 vs. Washington |
| RB Brian Robinson Jr. - Knee, Did Not Practice on Wednesday. Questionable for Week 6 at Baltimore |
OT Ronnie Stanley - Toe, Did Not Practice on Wednesday. Questionable for Week 6 vs. Washington |
| RB Austin Ekeler - Heel, Limited Practice on Wednesday. Questionable for Week 6 at Baltimore |
TE Charlie Kolar - Toe, Limited Practice on Wednesday. Questionable for Week 6 vs. Washington |
| SAF Percy Butler - Groin, Limited Practice on Wednesday. Questionable for Week 6 at Baltimore |
WR Deonte Harty - Knee, Limited Practice on Wednesday. Questionable for Week 6 vs. Washington |
| CB Jartavius Martin - Neck, Questionable for Week 6 at Baltimore |
WR Rashod Bateman - Groin, Did Not Practice on Wednesday. Questionable for Week 6 vs. Washington |
| WR Noah Brown - Groin, Limited Practice on Wednesday. Questionable for Week 6 at Baltimore |
LB Malik Harrison - Groin, Did Not Practice on Wednesday. Questionable for Week 6 vs. Washington |
| DE Clelin Ferrell - Knee, Did Not Practice on Wednesday. Questionable for Week 6 at Baltimore |
DT Broderick Washington - Knee, Did Not Practice on Wednesday. Questionable for Week 6 vs. Washington |
| DB Tyler Owens - Shin, Did Not Practice on Wednesday. Questionable for Week 6 at Baltimore |
RB Rasheen Ali - Neck, IR. Injured Reserve. Expected Return - Week 6 |
| DE Efe Obada - Lower Leg, Physically Unable to Perform. Expected Return - Week 6 |
CB Arthur Maulet - Knee, IR. Injured Reserve. Expected Return - Week 6 |
| LB Jordan Magee - Knee - Meniscus, IR. Injured Reserve. Expected Return - Week 6 |
CB Jalyn Armour-Davis - Hamstring, IR. Injured Reserve. Expected Return - Week 8 |
| WR Jamison Crowder - Calf, IR. Injured Reserve. Expected Return - Week 9 |
LB Deion Jennings - Undisclosed, IR. Injured Reserve |
| DT Norell Pollard - Undisclosed, IR. Injured Reserve |
CB Trayvon Mullen - Shoulder, IR. Injured Reserve |
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CB Christian Matthew - Undisclosed, IR. Injured Reserve |
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LB Malik Hamm - Knee - ACL, IR. Injured Reserve |
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RB Keaton Mitchell - Knee - ACL, Physically Unable to Perform. Expected Return - Week 9 |
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RB Owen Wright - Foot, IR. Injured Reserve |
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